1. Words of affirmation β IWILL
2. Sam's wife in "The Lord of the Rings" β ROSIE
3. Setting of the 1888 painting "CafΓ© Terrace at Night" β ARLES
4. Genre for Toots and the Maytals β SKA
5. Bishop for whom a neighborhood in Paris is named β STDENIS
6. Junk food that, ironically, has an exercise in its name β CHEESECURLS
7. Runs β AIRS
8. Rap figures, for short β MCS
9. Similarly β INKIND
10. Flash mob group, perhaps β DANCETROUPE
11. Decide where to stay β BOOKAROOM
12. One wearing the Star of Life emblem, for short β EMT
13. "Quite so" β TIS
15. Back in the race? β ENDORSE
21. French name meaning "born again" β RENE
23. "Mind your own beeswax!" β STAYOUTOFIT
24. It's not constructive β BADATTITUDE
25. Game division β TURN
26. "I saw that!" β HEY
28. Eccentric β DOTTY
29. Colorful capsule that splatters β PAINTBALL
31. Like samples β FREE
33. Appetizer β STARTER
34. Anchors might be seen on them β TVS
35. ___-Latino β AFRO
36. Funny Fred β ARMISEN
38. Picks up β SENSES
41. Literary protagonist who "generally gave herself very good advice (though she very seldom followed it)" β ALICE
42. Some hailstone "souvenirs" β DENTS
43. "Oof, sounds terrible!" β YEESH
45. Top-tier β AONE
47. Softball question β LOB
48. JosΓ© ___ (Mexican food brand) β OLE
49. Humble dwelling β HUT
50. Served as β WAS