1. Something a workaholic is unlikely to say → TGIF
2. Predator in a pod → ORCA
3. Point in a film when an iconic song sets the scene → NEEDLEDROP
4. Caught → SAW
5. The Onion's output → SATIRE
6. Provided entrees → OPENEDDOORS
7. Wild → FERAL
8. Mother of a hinny → ASS
9. Yosemite Sam's role in "Bugs Bunny's Christmas Carol" → EBENEZER
10. City across the Rio Grande from El Paso → JUAREZ
11. "No ___ mal" ("It's not bad," in Spanish) → ESTA
12. Repeated cry at a kegger → CHUG
13. Sort → TYPE
15. Channing of "Blink Twice" → TATUM
21. Hit the ceiling → ERUPT
23. Human rights lawyer Clooney → AMAL
24. "Wow, pretty sweet!" → THATSSOCOOL
25. Apt anagram of GAMES minus M → SEGA
26. Decorates → TRIMS
28. Emmy-winning actress for "The Bear" → AYOEDEBIRI
29. Get on (it) → HOPTO
32. "Hurry!" → RUN
34. A smartphone has many of these → USES
36. Suspicious looks → SIDEEYES
37. Island home of what may be the world's oldest living olive tree (2,000+ years) → CRETE
38. The U.A.E. is in it → OPEC
43. "Let me check with them" → ILLASK
45. Port of Spain? → PUERTO
46. Go up to → ENDAT
48. Good Neighbor or Design a Robot, e.g., in 35-Across → BADGE
49. Pull up → HALT
50. Purview → AREA
51. Founding member of 38-Down → IRAN
54. Easy triumph → ROUT
55. British monarch between William and George → ANNE
57. It's all around us → AIR
58. Spreadsheet feature → TAB